publication . Other literature type . Article . 2000

Histopathological characteristics of five clinical types of equine sarcoid

Jill Demeulemeester; Antoine De Moor; Richard Ducatelle; Ann Martens;
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  • Published: 01 Dec 2000
  • Publisher: Elsevier BV
Abstract
The purpose of this study was to determine the characteristics of occult, verrucous, fibroblastic, nodular and mixed equine sarcoids. Ten tumours of each type were examined histologically and analysed for the presence of bovine papilloma virus (BPV)- DNA. All tumours were positive for BPV - DNA and showed an increased density of dermal fibroblasts. Epidermal hyperplasia, hyperkeratosis, rete peg and 'picket fence' formation were only found consistently in the verrucous and mixed types and were often not present in occult and nodular sarcoids. Immunohistochemical staining for Keratins 10 and 16, Ki67 and p53 showed no important differences between the clinical ty...
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free text keywords: General Veterinary, Immunohistochemistry, Histology, Hyperkeratosis, medicine.disease, medicine, Pathology, medicine.medical_specialty, Hyperplasia, Equine sarcoids, Histopathology, Keratin, chemistry.chemical_classification, chemistry, Biology, Occult
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