publication . Other literature type . Article . 2007

MRI patterns of atrophy associated with progression to AD in amnestic mild cognitive impairment

Whitwell, Jl; Shiung, Mm; Przybelski, Sa; Weigand, Sd; Knopman, Ds; Boeve, Bf; Petersen, Rc; Clifford Jack;
Open Access English
  • Published: 26 Sep 2007
Objective: To compare the patterns of gray matter loss in subjects with amnestic mild cognitive impairment (aMCI) who progress to Alzheimer disease (AD) within a fixed clinical follow-up time vs those who remain stable. Methods: Twenty-one subjects with aMCI were identified from the Mayo Clinic Alzheimer9s research program who remained clinically stable for their entire observed clinical course (aMCI-S), where the minimum required follow-up time from MRI to last follow-up assessment was 3 years. These subjects were age- and gender-matched to 42 aMCI subjects who progressed to AD within 18 months of the MRI (aMCI-P). Each subject was then age- and gender-matched ...
Medical Subject Headings: mental disordersbehavioral disciplines and activities
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Europe PubMed Central
Other literature type . 2007
Provider: UnpayWall
Article . 2007
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