publication . Article . Other literature type . 2011

Developmental dysregulation of adult neurogenesis

Georg Kuhn, H.; Blomgren, K.;
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  • Published: 01 Mar 2011 Journal: European Journal of Neuroscience, volume 33, pages 1,115-1,122 (issn: 0953-816X, Copyright policy)
  • Publisher: Wiley
Abstract
Rather than a singular event that suddenly appears during adulthood, adult neurogenesis has long been recognized as the continuation of postnatal neurogenic activity. During the first postnatal weeks, significant cellular changes occur within and adjacent to germinal matrices of the subventricular zone and dentate gyrus. The majority of granule cells are generated during this period. In addition, radial glia are transformed into astrocyte-like stem cells, the ependymal layer is formed, and the highest rates of angiogenesis, gliogenesis and myelination are observed. The first postnatal weeks are critical as the brain growth rate is maximal, and changes during thi...
Subjects
Medical Subject Headings: sense organs
free text keywords: General Neuroscience, Stem cell, Brain growth, Subventricular zone, medicine.anatomical_structure, medicine, Angiogenesis, Dentate gyrus, Anatomy, Neural stem cell, Gliogenesis, Internal medicine, medicine.medical_specialty, Neuroscience, Endocrinology, Neurogenesis, Biology
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publication . Article . Other literature type . 2011

Developmental dysregulation of adult neurogenesis

Georg Kuhn, H.; Blomgren, K.;