publication . Other literature type . Article . 2013

A Systematic Review and Meta-analysis

Elizabeth Sumamo Schellenberg; Donna M. Dryden; Ben Vandermeer; Christine Ha; Christina Korownyk;
  • Published: 15 Oct 2013
  • Publisher: American College of Physicians
Data Synthesis: Nine randomized, controlled trials with patients who were at risk for diabetes and 11 with patients who had diabetes were included. Seven studies reported that lifestyle interventions decreased the risk for diabetes from the end of intervention up to 10 years after it. In patients with diabetes, 2 randomized, controlled trials (which included pharmacotherapy) reported no improvement in all-cause mortality (risk ratio, 0.75 [95% CI, 0.53 to 1.06]). Composite outcomes for cardiovascular disease were too heterogeneous to pool. One trial reported improvement in microvascular outcomes at 13-year follow-up.
free text keywords: Internal Medicine, General Medicine, Psychological intervention, Relative risk, Medicine, business.industry, business, Meta-analysis, Pharmacotherapy, Type 2 diabetes, medicine.disease, Disease, medicine.medical_specialty, Diabetes mellitus, Data synthesis, Cardiology
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