publication . Other literature type . Article . 2007

Analysis of protein complexes using mass spectrometry

Anne-Claude Gingras;
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  • Published: 01 Aug 2007
  • Publisher: Springer Science and Business Media LLC
Abstract
The combination of affinity purification and mass spectrometry (AP–MS) has recently been applied to the detailed characterization of protein complexes and large protein-interaction networks. Emerging AP–MS approaches promise a better understanding of protein-complex stoichiometry, structural organization and the dynamics of protein-complex composition. The versatile combination of affinity purification and mass spectrometry (AP–MS) has recently been applied to the detailed characterization of many protein complexes and large protein-interaction networks. The combination of AP–MS with other techniques, such as biochemical fractionation, intact mass measurement an...
Subjects
free text keywords: Cell Biology, Molecular Biology
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