publication . Article . Other literature type . 2011

Use of Florbetapir-PET for Imaging β-Amyloid Pathology

Clark, Christopher M.; Schneider, Julie A.; Bedell, Barry J.; Beach, Thomas G.; Bilker, Warren B.; Mintun, Mark A.; Pontecorvo, Michael J.; Hefti, Franz; Carpenter, Alan P.; Flitter, Matthew L.; ...
Open Access
  • Published: 19 Jan 2011 Journal: JAMA, volume 305, page 275 (issn: 0098-7484, Copyright policy)
  • Publisher: American Medical Association (AMA)
Abstract
CONTEXT: The ability to identify and quantify brain β-amyloid could increase the accuracy of a clinical diagnosis of Alzheimer disease. OBJECTIVE: To determine if florbetapir F 18 positron emission tomographic (PET) imaging performed during life accurately predicts the presence of β-amyloid in the brain at autopsy. DESIGN, SETTING, AND PARTICIPANTS: Prospective clinical evaluation conducted February 2009 through March 2010 of florbetapir-PET imaging performed on 35 patients from hospice, long-term care, and community health care facilities near the end of their lives (6 patients to establish the protocol and 29 to validate) compared with immunohistochemistry and...
Subjects
free text keywords: Autopsy, Anatomical pathology, medicine.medical_specialty, medicine, Medical imaging, Nuclear medicine, business.industry, business, Surgery, Dementia, medicine.disease, Positron emission tomography, medicine.diagnostic_test, Alzheimer's disease, Pathology, Florbetaben, Cohort, Article
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Europe PubMed Central
Other literature type . 2011
http://dx.doi.org/10.1001/jama...
Other literature type . 2011
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publication . Article . Other literature type . 2011

Use of Florbetapir-PET for Imaging β-Amyloid Pathology

Clark, Christopher M.; Schneider, Julie A.; Bedell, Barry J.; Beach, Thomas G.; Bilker, Warren B.; Mintun, Mark A.; Pontecorvo, Michael J.; Hefti, Franz; Carpenter, Alan P.; Flitter, Matthew L.; ...