publication . Article . Other literature type . 1985

Contribution of BAT and skeletal muscle to thermogenesis induced by ephedrine in man

Jens Bülow; Arne Astrup; Joop Madsen; Niels Johan Christensen;
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  • Published: 01 May 1985 Journal: American Journal of Physiology-Endocrinology and Metabolism, volume 248, pages E507-E515 (issn: 0193-1849, eissn: 1522-1555, Copyright policy)
  • Publisher: American Physiological Society
Abstract
<jats:p> This investigation was performed to examine the role of brown adipose tissue (BAT) in thermogenesis induced by ephedrine in man. Light microscopy of biopsies from necropsy cases showed BAT to occur most frequently in the perirenal fat. Perirenal BAT thermogenesis was investigated in five lean men before and during stimulation with 1 mg ephedrine orally X kg body wt-1. Perirenal BAT thermogenesis was assessed by continuous measurements of local temperature and blood flow with the 133xenon clearance method. In the same study the effect of ephedrine on skeletal muscle oxygen consumption was estimated by measurements of leg blood flow and arteriovenous oxyg...
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free text keywords: Physiology (medical), Physiology, Endocrinology, Diabetes and Metabolism, Catecholamine, medicine.drug, medicine, Adipose capsule of kidney, Arteriovenous oxygen difference, Skeletal muscle, medicine.anatomical_structure, Brown adipose tissue, Endocrinology, medicine.medical_specialty, Thermogenesis, Ephedrine, Adipose tissue, Biology, Internal medicine
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