publication . Article . Other literature type . 2008

Neural Correlates of Caregiver Burden in Cortical Basal Syndrome and Frontotemporal Dementia

Knutson, K.M.; Zamboni, G.; Tierney, M.C.; Grafman, J.;
English
  • Published: 01 Nov 2008 Journal: Dementia and geriatric cognitive disorders, volume 26, issue 5 (issn: 1420-8008, eissn: 1421-9824, Copyright policy)
  • Country: United Kingdom
Abstract
Aims: To determine areas of atrophy in patients that are associated with caregiver burden. Methods: We measured caregiver burden, dementia and neuropsychiatric scores in 22 patients with corticobasal syndrome (CBS) and 25 with frontotemporal dementia (FTD), and in 14 healthy controls. We used voxel-based morphometry to correlate caregiver burden with gray matter loss. Results: Increased dementia and behavioral disturbances contributed to higher burden scores in CBS patients, while behavioral disturbances alone significantly affected burden scores in frontal-variant FTD (FTD-fv) patients. In CBS patients, caregiver burden scores correlated with atrophy in left in...
Subjects
Medical Subject Headings: mental disordersnutritional and metabolic diseases
free text keywords: Cognitive Neuroscience, Geriatrics and Gerontology, Psychiatry and Mental health, Psychology, Dementia, medicine.disease, medicine, Caregiver burden, Cognitive disorder, Atrophy, Frontotemporal dementia, Psychiatry, medicine.medical_specialty, Basal ganglia disease, Voxel-based morphometry, Central nervous system disease, Original Research Article
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publication . Article . Other literature type . 2008

Neural Correlates of Caregiver Burden in Cortical Basal Syndrome and Frontotemporal Dementia

Knutson, K.M.; Zamboni, G.; Tierney, M.C.; Grafman, J.;