publication . Other literature type . Article . 2008

Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus

Ricardo C. Ferreira;
  • Published: 01 Aug 2008
  • Publisher: Springer Science and Business Media LLC
Abstract
Lindsey Criswell and colleagues report an association between three independent variants near TNFAIP3 and systemic lupus erythematosus (SLE). In a related study, Patrick Gaffney and colleagues report results of a genome-wide association study for SLE, also identifying variants in the TNFAIP3 region on 6q23 that are strongly associated with the disease. The same region on 6q23 has recently been associated with rheumatoid arthritis, but only a subset of risk alleles in this region seem to be common to both diseases.
Subjects
Medical Subject Headings: skin and connective tissue diseasesimmune system diseases
free text keywords: Article, Genetics, Disease, Autoimmune disease, medicine.disease, medicine, Rheumatoid arthritis, Bioinformatics, Systemic disease, Biology, Connective tissue disease, Immunopathology, Lupus erythematosus, TNFAIP3
Abstract
Lindsey Criswell and colleagues report an association between three independent variants near TNFAIP3 and systemic lupus erythematosus (SLE). In a related study, Patrick Gaffney and colleagues report results of a genome-wide association study for SLE, also identifying variants in the TNFAIP3 region on 6q23 that are strongly associated with the disease. The same region on 6q23 has recently been associated with rheumatoid arthritis, but only a subset of risk alleles in this region seem to be common to both diseases.
Subjects
Medical Subject Headings: skin and connective tissue diseasesimmune system diseases
free text keywords: Article, Genetics, Disease, Autoimmune disease, medicine.disease, medicine, Rheumatoid arthritis, Bioinformatics, Systemic disease, Biology, Connective tissue disease, Immunopathology, Lupus erythematosus, TNFAIP3
Powered by OpenAIRE Research Graph
Any information missing or wrong?Report an Issue