publication . Article . Other literature type . 2003

Response-monitoring dysfunction in aging and Alzheimer’s disease: an event-related potential study

Mathalon, Daniel H; Bennett, Amy; Askari, Nusha; Gray, E.Max; Rosenbloom, Margaret J; Ford, Judith M;
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  • Published: 01 Sep 2003 Journal: Neurobiology of Aging, volume 24, pages 675-685 (issn: 0197-4580, Copyright policy)
  • Publisher: Elsevier BV
Abstract
Abstract Executive control is a broad-reaching function that includes response monitoring and is likely implemented in the frontal lobes. Age- and dementia-related changes in response-monitoring were assessed during a Picture-Name Verification Task, using response-synchronized event-related potential (ERP) markers of response monitoring: the centrally oriented error-related negativity (ERN); the smaller and more frontally-oriented correct-response negativity (CRN); and the positivity associated with errors (Pe), a marker of error awareness. These were recorded from 10 younger and 10 older healthy controls, as well as 12 Alzheimer’s disease (AD) patients. Althoug...
Subjects
Medical Subject Headings: behavioral disciplines and activities
free text keywords: Developmental Biology, Ageing, General Neuroscience, Geriatrics and Gerontology, Clinical Neurology, Audiology, medicine.medical_specialty, medicine, Alzheimer's disease, medicine.disease, Internal medicine, Central nervous system disease, Dementia, Disease, Degenerative disease, Negativity effect, Event-related potential, Neuroscience, Senescence, Endocrinology, Psychology
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publication . Article . Other literature type . 2003

Response-monitoring dysfunction in aging and Alzheimer’s disease: an event-related potential study

Mathalon, Daniel H; Bennett, Amy; Askari, Nusha; Gray, E.Max; Rosenbloom, Margaret J; Ford, Judith M;