publication . Article . Other literature type . 2018

Transcriptome Profile in Unilateral Adrenalectomy-Induced Compensatory Adrenal Growth in the Rat

Piotr Celichowski; Marcin Rucinski; Karol Jopek;
Open Access English
  • Published: 07 Apr 2018 Journal: International Journal of Molecular Sciences, volume 19, issue 4 (eissn: 1422-0067, Copyright policy)
  • Publisher: MDPI
Abstract
Compensatory adrenal growth evoked by unilateral adrenalectomy (hemiadrenalectomy) constitutes one of the most frequently studied in vivo models of adrenocortical enlargement. This type of growth has been quite well characterized for its morphological, biochemical, and morphometric parameters. However, the molecular basis of compensatory adrenal growth is poorly understood. Therefore, the aim of this study was to investigate the rat adrenal transcriptome profile during the time of two previously described adrenocortical proliferation waves at 24 and 72 h after unilateral adrenalectomy. Surgical removal of the left adrenal or a sham operation was accomplished via...
Subjects
free text keywords: Article, rat, adrenal gland, gene expression profile, compensatory adrenal growth, unilateral adrenalectomy, gene ontology, Biology (General), QH301-705.5, Chemistry, QD1-999, Physical and Theoretical Chemistry, Inorganic Chemistry, Organic Chemistry, Spectroscopy, Molecular Biology, Catalysis, General Medicine, Computer Science Applications
49 references, page 1 of 4

Dallman, M.F.. Control of adrenocortical growth in vivo. Endocr. Res.. 1984; 10: 213-242 [OpenAIRE] [PubMed] [DOI]

Majchrzak, M., Malendowicz, L.K.. Sex differences in adrenocortical structure and function. XII. Stereologic studies of rat adrenal cortex in the course of maturation. Cell Tissue Res.. 1983; 232: 457-469 [PubMed] [DOI]

Nikicicz, H., Kasprzak, A., Majchrzak, M., Malendowicz, L.K.. Sex differences in adrenocortical structure and function. XVII. Analysis of adrenal growth rate in maturing male and female rats and hamsters. Gegenbaurs Morphol. Jahrb.. 1984; 130: 573-582 [OpenAIRE] [PubMed]

Mackay, E.M., Mackay, L.L.. Compensatory Hypertrophy of the Adrenal Cortex. J. Exp. Med.. 1926; 43: 395-402 [OpenAIRE] [PubMed] [DOI]

Nussdorfer, G.G.. Cytophysiology of the adrenal cortex. Int. Rev. Cytol.. 1986; 98: 1-405 [OpenAIRE] [PubMed]

Ehrhart-Bornstein, M., Hinson, J.P., Bornstein, S.R., Scherbaum, W.A., Vinson, G.P.. Intraadrenal interactions in the regulation of adrenocortical steroidogenesis. Endocr. Rev.. 1998; 19: 101-143 [OpenAIRE] [PubMed] [DOI]

Vinson, G.P., Hinson, J.P., Toth, I.E.. The neuroendocrinology of the adrenal cortex. J. Neuroendocrinol.. 1994; 6: 235-246 [OpenAIRE] [PubMed] [DOI]

Ehrhart-Bornstein, M., Bornstein, S.R., Scherbaum, W.A.. Sympathoadrenal system and immune system in the regulation of adrenocortical function. Eur. J. Endocrinol.. 1996; 135: 19-26 [OpenAIRE] [PubMed] [DOI]

Engeland, W.C., Arnhold, M.M.. Neural circuitry in the regulation of adrenal corticosterone rhythmicity. Endocrine. 2005; 28: 325-332 [OpenAIRE] [PubMed] [DOI]

Hornsby, P.J., Winter, J.S.D.. 1—The regulation of adrenocortical function by control of growth and structure. Adrenal Cortex. 1985: 1-31

McNicol, A.M., Duffy, A.E., Penman, I.D.. Compensatory adrenal growth in dexamethasone treated rats. Virchows Arch. B. 1989; 56: 317-320 [PubMed] [DOI]

Malendowicz, L.K., Guidolin, D., Trejter, M., Rucinski, M., Porzionato, A., de Caro, R., Nowak, M.. Neuromedin-U inhibits unilateral adrenalectomy-induced compensatory adrenal growth in the rat. Peptides. 2009; 30: 935-939 [OpenAIRE] [PubMed] [DOI]

Edwards, A.V., Jones, C.T.. The effect of splanchnic nerve stimulation on adrenocortical activity in conscious calves. J. Physiol.. 1987; 382: 385-396 [OpenAIRE] [PubMed] [DOI]

Edwards, A.V., Jones, C.T., Bloom, S.R.. Reduced adrenal cortical sensitivity to ACTH in lambs with cut splanchnic nerves. J. Endocrinol.. 1986; 110: 81-85 [OpenAIRE] [PubMed] [DOI]

Dijkstra, I., Binnekade, R., Tilders, F.J.. Diurnal variation in resting levels of corticosterone is not mediated by variation in adrenal responsiveness to adrenocorticotropin but involves splanchnic nerve integrity. Endocrinology. 1996; 137: 540-547 [OpenAIRE] [PubMed] [DOI]

49 references, page 1 of 4
Abstract
Compensatory adrenal growth evoked by unilateral adrenalectomy (hemiadrenalectomy) constitutes one of the most frequently studied in vivo models of adrenocortical enlargement. This type of growth has been quite well characterized for its morphological, biochemical, and morphometric parameters. However, the molecular basis of compensatory adrenal growth is poorly understood. Therefore, the aim of this study was to investigate the rat adrenal transcriptome profile during the time of two previously described adrenocortical proliferation waves at 24 and 72 h after unilateral adrenalectomy. Surgical removal of the left adrenal or a sham operation was accomplished via...
Subjects
free text keywords: Article, rat, adrenal gland, gene expression profile, compensatory adrenal growth, unilateral adrenalectomy, gene ontology, Biology (General), QH301-705.5, Chemistry, QD1-999, Physical and Theoretical Chemistry, Inorganic Chemistry, Organic Chemistry, Spectroscopy, Molecular Biology, Catalysis, General Medicine, Computer Science Applications
49 references, page 1 of 4

Dallman, M.F.. Control of adrenocortical growth in vivo. Endocr. Res.. 1984; 10: 213-242 [OpenAIRE] [PubMed] [DOI]

Majchrzak, M., Malendowicz, L.K.. Sex differences in adrenocortical structure and function. XII. Stereologic studies of rat adrenal cortex in the course of maturation. Cell Tissue Res.. 1983; 232: 457-469 [PubMed] [DOI]

Nikicicz, H., Kasprzak, A., Majchrzak, M., Malendowicz, L.K.. Sex differences in adrenocortical structure and function. XVII. Analysis of adrenal growth rate in maturing male and female rats and hamsters. Gegenbaurs Morphol. Jahrb.. 1984; 130: 573-582 [OpenAIRE] [PubMed]

Mackay, E.M., Mackay, L.L.. Compensatory Hypertrophy of the Adrenal Cortex. J. Exp. Med.. 1926; 43: 395-402 [OpenAIRE] [PubMed] [DOI]

Nussdorfer, G.G.. Cytophysiology of the adrenal cortex. Int. Rev. Cytol.. 1986; 98: 1-405 [OpenAIRE] [PubMed]

Ehrhart-Bornstein, M., Hinson, J.P., Bornstein, S.R., Scherbaum, W.A., Vinson, G.P.. Intraadrenal interactions in the regulation of adrenocortical steroidogenesis. Endocr. Rev.. 1998; 19: 101-143 [OpenAIRE] [PubMed] [DOI]

Vinson, G.P., Hinson, J.P., Toth, I.E.. The neuroendocrinology of the adrenal cortex. J. Neuroendocrinol.. 1994; 6: 235-246 [OpenAIRE] [PubMed] [DOI]

Ehrhart-Bornstein, M., Bornstein, S.R., Scherbaum, W.A.. Sympathoadrenal system and immune system in the regulation of adrenocortical function. Eur. J. Endocrinol.. 1996; 135: 19-26 [OpenAIRE] [PubMed] [DOI]

Engeland, W.C., Arnhold, M.M.. Neural circuitry in the regulation of adrenal corticosterone rhythmicity. Endocrine. 2005; 28: 325-332 [OpenAIRE] [PubMed] [DOI]

Hornsby, P.J., Winter, J.S.D.. 1—The regulation of adrenocortical function by control of growth and structure. Adrenal Cortex. 1985: 1-31

McNicol, A.M., Duffy, A.E., Penman, I.D.. Compensatory adrenal growth in dexamethasone treated rats. Virchows Arch. B. 1989; 56: 317-320 [PubMed] [DOI]

Malendowicz, L.K., Guidolin, D., Trejter, M., Rucinski, M., Porzionato, A., de Caro, R., Nowak, M.. Neuromedin-U inhibits unilateral adrenalectomy-induced compensatory adrenal growth in the rat. Peptides. 2009; 30: 935-939 [OpenAIRE] [PubMed] [DOI]

Edwards, A.V., Jones, C.T.. The effect of splanchnic nerve stimulation on adrenocortical activity in conscious calves. J. Physiol.. 1987; 382: 385-396 [OpenAIRE] [PubMed] [DOI]

Edwards, A.V., Jones, C.T., Bloom, S.R.. Reduced adrenal cortical sensitivity to ACTH in lambs with cut splanchnic nerves. J. Endocrinol.. 1986; 110: 81-85 [OpenAIRE] [PubMed] [DOI]

Dijkstra, I., Binnekade, R., Tilders, F.J.. Diurnal variation in resting levels of corticosterone is not mediated by variation in adrenal responsiveness to adrenocorticotropin but involves splanchnic nerve integrity. Endocrinology. 1996; 137: 540-547 [OpenAIRE] [PubMed] [DOI]

49 references, page 1 of 4
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