publication . Article . 2003

protective effects of ferulic acid on hyperlipidemic diabetic rats

Rukkumani R;
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  • Published: 01 Sep 2003 Journal: Acta Diabetologica, volume 40, pages 118-122 (issn: 0940-5429, eissn: 1432-5233, Copyright policy)
  • Publisher: Springer Science and Business Media LLC
Abstract
Diabetes, when uncontrolled, causes dyslipidemia often followed by atherogenic abnormalities. The present study was focused to determine whether ferulic acid (FA), a flavonoid, has any role to play in diabetes-induced dyslipidemia. Diabetes in rats was induced with streptozotocin. The levels of blood glucose and plasma triglycerides (TG), free fatty acids (FFA), cholesterol and phospholipids were elevated during diabetes. Treatment with FA significantly reduced the elevated plasma lipid and blood glucose levels; a more pronounced effect was found with low-dose ferulic acid than with high dose. Thus, our study demonstrates that ferulic acid lowers the lipid level...
Subjects
free text keywords: Internal Medicine, Endocrinology, Diabetes and Metabolism, Endocrinology, General Medicine, medicine.medical_specialty, medicine, Cholesterol, chemistry.chemical_compound, chemistry, Flavonoid, chemistry.chemical_classification, Streptozotocin, medicine.drug, business.industry, business, Diabetes mellitus, medicine.disease, Ferulic acid, Dyslipidemia, Hyperlipidemia
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