publication . Other literature type . Article . 2011

Massive genomic decay in Serratia symbiotica, a recently evolved symbiont of aphids.

Gaelen R. Burke; Nancy A. Moran;
Open Access
  • Published: 01 Jan 2011
  • Publisher: Oxford University Press (OUP)
Abstract
All vertically transmitted bacterial symbionts undergo a process of genome reduction over time, resulting in tiny, gene-dense genomes. Comparison of genomes of ancient bacterial symbionts gives only limited information about the early stages in the transition from a free-living to symbiotic lifestyle because many changes become obscured over time. Here, we present the genome sequence for the recently evolved aphid symbiont Serratia symbiotica. The S. symbiotica genome exhibits several of the hallmarks of genome evolution observed in more ancient symbionts, including elevated rates of evolution and reduction in genome size. The genome also shows evidence for mass...
Read more
doi: 10.1093/gbe/evr002
pmc: PMC3056288
pmid: 21266540
Subjects
free text keywords: Genetics, Ecology, Evolution, Behavior and Systematics, Research Articles, Serratia symbiotica, genome reduction, recent symbiont, Whole genome sequencing, Pseudogene, Genome evolution, Genomics, Biology, Bacterial genome size, Genome, Genome size, Gene
Related Organizations
View more
Funded by
NSF| Biocomplexity in the Environment/GEN-EN: Response of Host and Symbiont Genomes to Environmental Stress and its Ecological Consequences
Project
Biocomplexity in the Environment/GEN-EN: Response of Host and Symbiont Genomes to Environmental Stress and its Ecological Consequences
  • Funder: National Science Foundation (NSF)
  • Project Code: 0313737
  • Funding stream: Directorate for Biological Sciences | Emerging Frontiers Office
, NSF| En-Gen: Mutation in Genomes of Obligate Symbionts and Impacts on the Ecological Tolerances and Distributions of Hosts: Buchnera and Pea Aphids
Project
En-Gen: Mutation in Genomes of Obligate Symbionts and Impacts on the Ecological Tolerances and Distributions of Hosts: Buchnera and Pea Aphids
  • Funder: National Science Foundation (NSF)
  • Project Code: 0723472
  • Funding stream: Directorate for Biological Sciences | Emerging Frontiers Office
Download fromView all 3 versions
Genome Biology and Evolution
Article . 2011
Provider: Crossref
Genome Biology and Evolution
Article
Provider: UnpayWall
Genome Biology and Evolution
Article
Provider: Microsoft Academic Graph
Europe PubMed Central
Article . 2011
Provider: PubMed Central
View more
76 references, page 1 of 6

Akman Gündüz, E, Douglas, AE. Symbiotic bacteria enable insect to use a nutritionally inadequate diet. Proc Biol Sci. 2009; 276: 987-991 [OpenAIRE] [PubMed]

Baldo, L, Bordenstein, S, Wernegreen, JJ, Werren, JH. Widespread recombination throughout Wolbachia genomes. Mol Biol Evol. 2006; 23: 437-449 [OpenAIRE] [PubMed]

Baumann, P. Biology of bacteriocyte-associated endosymbionts of plant sap-sucking insects. Annu Rev Microbiol. 2005; 59: 155-189 [PubMed]

Belda, E, Moya, A, Bentley, S, Silva, FJ. Mobile genetic element proliferation and gene inactivation impact over the genome structure and metabolic capabilities of Sodalis glossinidius, the secondary endosymbiont of tsetse flies. BMC Genomics. 2010; 11: 449 [OpenAIRE] [PubMed]

Birney, E, Clamp, M, Durbin, R. GeneWise and genomewise. Genome Res. 2004; 14: 988-995 [OpenAIRE] [PubMed]

Bordenstein, SR, Reznikoff, WS. Mobile DNA in obligate intracellular bacteria. Nat Rev Microbiol. 2005; 3: 688-699 [OpenAIRE] [PubMed]

Buchner, P. Endosymbionts of animals with plant microorganisms. 1965

Burke, G, Fiehn, O, Moran, N. Effects of facultative symbionts and heat stress on the metabolome of pea aphids. ISME J. 2010; 4: 242-252 [PubMed]

Burke, GR, Normark, BB, Favret, C, Moran, NA. Evolution and diversity of facultative symbionts from the aphid subfamily Lachninae. Appl Environ Microbiol. 2009; 75: 5328-5335 [OpenAIRE] [PubMed]

Caspi, R. The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases. Nucleic Acids Res. 2010; 38 (Database issue): D473-D479 [OpenAIRE] [PubMed]

Chen, DQ, Montllor, CB, Purcell, AH. Fitness effects of two facultative endosymbiotic bacteria on the pea aphid, Acyrthosiphon pisum, and the blue alfalfa aphid, A. kondoi. Entomol Exp Appl. 2000; 95: 315-323 [OpenAIRE]

Cho, N-K. The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host-cell interaction genes. Proc Natl Acad Sci U S A. 2007; 104: 7981-7986 [OpenAIRE] [PubMed]

Clark, MA, Moran, NA, Baumann, P. Sequence evolution in bacterial endosymbionts having extreme base compositions. Mol Biol Evol. 1999; 16: 1586-1598 [OpenAIRE] [PubMed]

Cole, ST. Massive gene decay in the leprosy bacillus. Nature. 2001; 409: 1007-1011 [PubMed]

Degnan, PH, Moran, NA. Evolutionary genetics of a defensive facultative symbiont of aphids: exchange of toxin-encoding bacteriophage. Mol Ecol. 2007; 17: 916-929 [OpenAIRE] [PubMed]

76 references, page 1 of 6
Related research
Abstract
All vertically transmitted bacterial symbionts undergo a process of genome reduction over time, resulting in tiny, gene-dense genomes. Comparison of genomes of ancient bacterial symbionts gives only limited information about the early stages in the transition from a free-living to symbiotic lifestyle because many changes become obscured over time. Here, we present the genome sequence for the recently evolved aphid symbiont Serratia symbiotica. The S. symbiotica genome exhibits several of the hallmarks of genome evolution observed in more ancient symbionts, including elevated rates of evolution and reduction in genome size. The genome also shows evidence for mass...
Read more
doi: 10.1093/gbe/evr002
pmc: PMC3056288
pmid: 21266540
Subjects
free text keywords: Genetics, Ecology, Evolution, Behavior and Systematics, Research Articles, Serratia symbiotica, genome reduction, recent symbiont, Whole genome sequencing, Pseudogene, Genome evolution, Genomics, Biology, Bacterial genome size, Genome, Genome size, Gene
Related Organizations
View more
Funded by
NSF| Biocomplexity in the Environment/GEN-EN: Response of Host and Symbiont Genomes to Environmental Stress and its Ecological Consequences
Project
Biocomplexity in the Environment/GEN-EN: Response of Host and Symbiont Genomes to Environmental Stress and its Ecological Consequences
  • Funder: National Science Foundation (NSF)
  • Project Code: 0313737
  • Funding stream: Directorate for Biological Sciences | Emerging Frontiers Office
, NSF| En-Gen: Mutation in Genomes of Obligate Symbionts and Impacts on the Ecological Tolerances and Distributions of Hosts: Buchnera and Pea Aphids
Project
En-Gen: Mutation in Genomes of Obligate Symbionts and Impacts on the Ecological Tolerances and Distributions of Hosts: Buchnera and Pea Aphids
  • Funder: National Science Foundation (NSF)
  • Project Code: 0723472
  • Funding stream: Directorate for Biological Sciences | Emerging Frontiers Office
Download fromView all 3 versions
Genome Biology and Evolution
Article . 2011
Provider: Crossref
Genome Biology and Evolution
Article
Provider: UnpayWall
Genome Biology and Evolution
Article
Provider: Microsoft Academic Graph
Europe PubMed Central
Article . 2011
Provider: PubMed Central
View more
76 references, page 1 of 6

Akman Gündüz, E, Douglas, AE. Symbiotic bacteria enable insect to use a nutritionally inadequate diet. Proc Biol Sci. 2009; 276: 987-991 [OpenAIRE] [PubMed]

Baldo, L, Bordenstein, S, Wernegreen, JJ, Werren, JH. Widespread recombination throughout Wolbachia genomes. Mol Biol Evol. 2006; 23: 437-449 [OpenAIRE] [PubMed]

Baumann, P. Biology of bacteriocyte-associated endosymbionts of plant sap-sucking insects. Annu Rev Microbiol. 2005; 59: 155-189 [PubMed]

Belda, E, Moya, A, Bentley, S, Silva, FJ. Mobile genetic element proliferation and gene inactivation impact over the genome structure and metabolic capabilities of Sodalis glossinidius, the secondary endosymbiont of tsetse flies. BMC Genomics. 2010; 11: 449 [OpenAIRE] [PubMed]

Birney, E, Clamp, M, Durbin, R. GeneWise and genomewise. Genome Res. 2004; 14: 988-995 [OpenAIRE] [PubMed]

Bordenstein, SR, Reznikoff, WS. Mobile DNA in obligate intracellular bacteria. Nat Rev Microbiol. 2005; 3: 688-699 [OpenAIRE] [PubMed]

Buchner, P. Endosymbionts of animals with plant microorganisms. 1965

Burke, G, Fiehn, O, Moran, N. Effects of facultative symbionts and heat stress on the metabolome of pea aphids. ISME J. 2010; 4: 242-252 [PubMed]

Burke, GR, Normark, BB, Favret, C, Moran, NA. Evolution and diversity of facultative symbionts from the aphid subfamily Lachninae. Appl Environ Microbiol. 2009; 75: 5328-5335 [OpenAIRE] [PubMed]

Caspi, R. The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases. Nucleic Acids Res. 2010; 38 (Database issue): D473-D479 [OpenAIRE] [PubMed]

Chen, DQ, Montllor, CB, Purcell, AH. Fitness effects of two facultative endosymbiotic bacteria on the pea aphid, Acyrthosiphon pisum, and the blue alfalfa aphid, A. kondoi. Entomol Exp Appl. 2000; 95: 315-323 [OpenAIRE]

Cho, N-K. The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host-cell interaction genes. Proc Natl Acad Sci U S A. 2007; 104: 7981-7986 [OpenAIRE] [PubMed]

Clark, MA, Moran, NA, Baumann, P. Sequence evolution in bacterial endosymbionts having extreme base compositions. Mol Biol Evol. 1999; 16: 1586-1598 [OpenAIRE] [PubMed]

Cole, ST. Massive gene decay in the leprosy bacillus. Nature. 2001; 409: 1007-1011 [PubMed]

Degnan, PH, Moran, NA. Evolutionary genetics of a defensive facultative symbiont of aphids: exchange of toxin-encoding bacteriophage. Mol Ecol. 2007; 17: 916-929 [OpenAIRE] [PubMed]

76 references, page 1 of 6
Related research
Powered by OpenAIRE Research Graph
Any information missing or wrong?Report an Issue