publication . Other literature type . Article . 2002

Does adenosine prevent myocardial micronecrosis following percutaneous coronary intervention? The ADELINE pilot trial

Desmet, W J R; Dens, J; Coussement, P; Van de Werf, F;
Open Access English
  • Published: 01 Sep 2002
  • Publisher: Copyright 2002 by Heart
Abstract
After successful percutaneous coronary intervention (PCI), 24–44% of patients suffer some myocardial damage as indicated by a significant change in the concentrations of cardiospecific troponin or the MB isoenzyme of creatine kinase (CK-MB).1,2 Patients with minor increases of these cardiac markers after PCI constitute a population with a worse long term prognosis.3 Preconditioning of human myocardium can be obtained by intracoronary administration of adenosine, as indicated by attenuation of ischaemia and chest pain in patients undergoing PCI.4 In the present trial (ADELINE, does ADEnosine Limit myocardial Necrosis), we investigated the effect of intracoronary ...
Subjects
Medical Subject Headings: cardiovascular diseases
free text keywords: Scientific Letters, Myocardial infarction, medicine.disease, medicine, Interventional cardiology, medicine.medical_specialty, Chest pain, medicine.symptom, Cardiology, Creatine kinase, biology.protein, biology, Percutaneous coronary intervention, medicine.medical_treatment, Population, education.field_of_study, education, Internal medicine, Conventional PCI, business.industry, business, Troponin, Anesthesia
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Other literature type . 2002
Heart
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Heart
Article . 2002
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