publication . Article . Other literature type . 2013

Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials

V. L. Gloy; M. Briel; D. L. Bhatt; S. R. Kashyap; P. R. Schauer; G. Mingrone; H. C. Bucher; A. J. Nordmann;
Open Access English
  • Published: 22 Oct 2013 Journal: The BMJ, volume 347 (issn: 0959-8138, eissn: 1756-1833, Copyright policy)
  • Publisher: BMJ Publishing Group Ltd.
  • Country: United States
Abstract
Objective To quantify the overall effects of bariatric surgery compared with non-surgical treatment for obesity. Design Systematic review and meta-analysis based on a random effects model. Data sources Searches of Medline, Embase, and the Cochrane Library from their inception to December 2012 regardless of language or publication status. Eligibility criteria Eligible studies were randomised controlled trials with ≥6 months of follow-up that included individuals with a body mass index ≥30, compared current bariatric surgery techniques with non-surgical treatment, and reported on body weight, cardiovascular risk factors, quality of life, or adverse events. Results...
Subjects
free text keywords: Research, Weight loss, medicine.symptom, medicine, Body mass index, Obesity, medicine.disease, Type 2 diabetes, Cochrane Library, Meta-analysis, Surgery, medicine.medical_specialty, Relative risk, business.industry, business, Adverse effect
44 references, page 1 of 3

1 Bhatt DL, Steg PG, Ohman EM, Hirsch AT, Ikeda Y, Mas JL, et al. International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis. JAMA 2006;295:180-9.16403930 [PubMed]

2 Lobstein T, Leach RJ. Tackling obesities: future choices. International comparisons of obesity trends, determinants and responses—evidence review. www.bis.gov.uk/assets/foresight/docs/obesity/06%20page.pdf.

3 World Health Organization. WHO global database on body mass index. http://apps.who.int/bmi/index.jsp.

4 Picot J, Jones J, Colquitt JL, Gospodarevskaya E, Loveman E, Baxter L, et al. The clinical effectiveness and cost-effectiveness of bariatric (weight loss) surgery for obesity: a systematic review and economic evaluation. Health Technol Assess 2009;13:1-190, 215-357, iii-iv.

5 Allender S, Rayner M. The burden of overweight and obesity-related ill health in the UK. Obes Rev 2007;8:467-73.17716304 [PubMed]

6 National Institute of Health. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults—the evidence report. www.nhlbi.nih.gov/guidelines/obesity/ob_gdlns.htm 1998.

7 Papamargaritis D, Pournaras D, le Roux CW. Techniques, assessment, and effectiveness of bariatric surgery in combating obesity. Open Access Surgery 2010;3.

8 Dixon JB, le Roux CW, Rubino F, Zimmet P. Bariatric surgery for type 2 diabetes. Lancet 2012;379:2300-11.22683132 [PubMed]

9 Buchwald H, Oien DM. Metabolic/bariatric surgery worldwide 2011. Obes Surg 2013;23:427-36.23338049 [PubMed]

10 Poirier P, Cornier MA, Mazzone T, Stiles S, Cummings S, Klein S, et al. Bariatric surgery and cardiovascular risk factors: a scientific statement from the American Heart Association. Circulation 2011;123:1683-701.21403092 [PubMed]

11 Colquitt JL, Picot J, Loveman E, Clegg AJ. Surgery for obesity. Cochrane Database Syst Rev 2009;(2):CD003641.

12 Padwal R, Klarenbach S, Wiebe N, Birch D, Karmali S, Manns B, et al. Bariatric surgery: a systematic review and network meta-analysis of randomized trials. Obes Rev 2011;12:602-21.21438991 [PubMed]

13 Higgins JPT, Green S. Cochrane handbook for systematic reviews of interventions. Cochrane Collaboration, 2011 www.cochrane.org/training/cochrane-handbook.

14 Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:629-34.9310563 [OpenAIRE] [PubMed]

15 Wiebe N, Vandermeer B, Platt RW, Klassen TP, Moher D, Barrowman NJ. A systematic review identifies a lack of standardization in methods for handling missing variance data. J Clin Epidemiol 2006;59:342-53.16549255 [PubMed]

44 references, page 1 of 3
Abstract
Objective To quantify the overall effects of bariatric surgery compared with non-surgical treatment for obesity. Design Systematic review and meta-analysis based on a random effects model. Data sources Searches of Medline, Embase, and the Cochrane Library from their inception to December 2012 regardless of language or publication status. Eligibility criteria Eligible studies were randomised controlled trials with ≥6 months of follow-up that included individuals with a body mass index ≥30, compared current bariatric surgery techniques with non-surgical treatment, and reported on body weight, cardiovascular risk factors, quality of life, or adverse events. Results...
Subjects
free text keywords: Research, Weight loss, medicine.symptom, medicine, Body mass index, Obesity, medicine.disease, Type 2 diabetes, Cochrane Library, Meta-analysis, Surgery, medicine.medical_specialty, Relative risk, business.industry, business, Adverse effect
44 references, page 1 of 3

1 Bhatt DL, Steg PG, Ohman EM, Hirsch AT, Ikeda Y, Mas JL, et al. International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis. JAMA 2006;295:180-9.16403930 [PubMed]

2 Lobstein T, Leach RJ. Tackling obesities: future choices. International comparisons of obesity trends, determinants and responses—evidence review. www.bis.gov.uk/assets/foresight/docs/obesity/06%20page.pdf.

3 World Health Organization. WHO global database on body mass index. http://apps.who.int/bmi/index.jsp.

4 Picot J, Jones J, Colquitt JL, Gospodarevskaya E, Loveman E, Baxter L, et al. The clinical effectiveness and cost-effectiveness of bariatric (weight loss) surgery for obesity: a systematic review and economic evaluation. Health Technol Assess 2009;13:1-190, 215-357, iii-iv.

5 Allender S, Rayner M. The burden of overweight and obesity-related ill health in the UK. Obes Rev 2007;8:467-73.17716304 [PubMed]

6 National Institute of Health. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults—the evidence report. www.nhlbi.nih.gov/guidelines/obesity/ob_gdlns.htm 1998.

7 Papamargaritis D, Pournaras D, le Roux CW. Techniques, assessment, and effectiveness of bariatric surgery in combating obesity. Open Access Surgery 2010;3.

8 Dixon JB, le Roux CW, Rubino F, Zimmet P. Bariatric surgery for type 2 diabetes. Lancet 2012;379:2300-11.22683132 [PubMed]

9 Buchwald H, Oien DM. Metabolic/bariatric surgery worldwide 2011. Obes Surg 2013;23:427-36.23338049 [PubMed]

10 Poirier P, Cornier MA, Mazzone T, Stiles S, Cummings S, Klein S, et al. Bariatric surgery and cardiovascular risk factors: a scientific statement from the American Heart Association. Circulation 2011;123:1683-701.21403092 [PubMed]

11 Colquitt JL, Picot J, Loveman E, Clegg AJ. Surgery for obesity. Cochrane Database Syst Rev 2009;(2):CD003641.

12 Padwal R, Klarenbach S, Wiebe N, Birch D, Karmali S, Manns B, et al. Bariatric surgery: a systematic review and network meta-analysis of randomized trials. Obes Rev 2011;12:602-21.21438991 [PubMed]

13 Higgins JPT, Green S. Cochrane handbook for systematic reviews of interventions. Cochrane Collaboration, 2011 www.cochrane.org/training/cochrane-handbook.

14 Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:629-34.9310563 [OpenAIRE] [PubMed]

15 Wiebe N, Vandermeer B, Platt RW, Klassen TP, Moher D, Barrowman NJ. A systematic review identifies a lack of standardization in methods for handling missing variance data. J Clin Epidemiol 2006;59:342-53.16549255 [PubMed]

44 references, page 1 of 3
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