publication . Other literature type . Article . 2013

Adult neurogenesis in the mammalian hippocampus: Why the dentate gyrus?

L. J. Drew; S. Fusi; R. Hen;
Open Access English
  • Published: 19 Nov 2013
  • Publisher: Cold Spring Harbor Laboratory Press
Abstract
In the adult mammalian brain, newly generated neurons are continuously incorporated into two networks: interneurons born in the subventricular zone migrate to the olfactory bulb, whereas the dentate gyrus (DG) of the hippocampus integrates locally born principal neurons. That the rest of the mammalian brain loses significant neurogenic capacity after the perinatal period suggests that unique aspects of the structure and function of DG and olfactory bulb circuits allow them to benefit from the adult generation of neurons. In this review, we consider the distinctive features of the DG that may account for it being able to profit from this singular form of neural p...
Subjects
Medical Subject Headings: nervous system
free text keywords: Review, Cognitive Neuroscience, Cellular and Molecular Neuroscience, Neuropsychology and Physiological Psychology, Hippocampus, Neurogenesis, Neuropoiesis, Olfactory bulb, Psychology, Subventricular zone, medicine.anatomical_structure, medicine, Dentate gyrus, Neuroplasticity, Developmental psychology, Neuroscience, Neural stem cell
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publication . Other literature type . Article . 2013

Adult neurogenesis in the mammalian hippocampus: Why the dentate gyrus?

L. J. Drew; S. Fusi; R. Hen;