publication . Other literature type . Article . 2012

The U-Box/ARM E3 Ligase PUB13 Regulates Cell Death, Defense, and Flowering Time in Arabidopsis

Wei Li; Il-Pyung Ahn; Yuese Ning; Chan-Ho Park; Lirong Zeng; Justin G A Whitehill; Haibin Lu; Qingzhen Zhao; Bo Ding; Qi Xie; ...
  • Published: 01 Mar 2012
  • Publisher: American Society of Plant Biologists (ASPB)
The components in plant signal transduction pathways are intertwined and affect each other to coordinate plant growth, development, and defenses to stresses. The role of ubiquitination in connecting these pathways, particularly plant innate immunity and flowering, is largely unknown. Here, we report the dual roles for the Arabidopsis (Arabidopsis thaliana) Plant U-box protein13 (PUB13) in defense and flowering time control. In vitro ubiquitination assays indicated that PUB13 is an active E3 ubiquitin ligase and that the intact U-box domain is required for the E3 ligase activity. Disruption of the PUB13 gene by T-DNA insertion results in spontaneous cell death, t...
Medical Subject Headings: food and beveragesfungi
free text keywords: Plant Science, Genetics, Physiology, Biology, Ubiquitin, biology.protein, Innate immune system, Botany, Ubiquitin ligase, Signal transduction, Arabidopsis, biology.organism_classification, Programmed cell death, Arabidopsis thaliana, Flowering Locus C, Plants Interacting with Other Organisms
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