publication . Article . Other literature type . 2013

Toward the future of psychiatric diagnosis: the seven pillars of RDoC

Cuthbert, Bruce N; Insel, Thomas R;
Open Access
  • Published: 14 May 2013 Journal: BMC Medicine, volume 11 (eissn: 1741-7015, Copyright policy)
  • Publisher: Springer Science and Business Media LLC
Abstract
Background Current diagnostic systems for mental disorders rely upon presenting signs and symptoms, with the result that current definitions do not adequately reflect relevant neurobiological and behavioral systems - impeding not only research on etiology and pathophysiology but also the development of new treatments. Discussion The National Institute of Mental Health began the Research Domain Criteria (RDoC) project in 2009 to develop a research classification system for mental disorders based upon dimensions of neurobiology and observable behavior. RDoC supports research to explicate fundamental biobehavioral dimensions that cut across current heterogeneous di...
Subjects
free text keywords: General Medicine, Medicine(all), Debate, Diagnosis, DSM, ICD, Psychiatric diagnosis, Psychopathology, RDoC, Research domain criteria
35 references, page 1 of 3

Wing, L, Gould, J, Gillberg, C. Autism spectrum disorders in the DSM-V: better or worse than the DSM-IV?. Res Dev Disabil. 2011; 32: 768-773 [OpenAIRE] [PubMed] [DOI]

Friedman, RA. Grief, depression, and the DSM-5. N Engl J Med. 2012; 366: 1855-1857 [PubMed] [DOI]

Skodol, AE. Personality disorders in DSM-5. Annual Rev of Clinical Psychology. 2012; 8: 317-344 [OpenAIRE] [DOI]

Clarkin, JF, Huprich, SK. Do DSM-5 personality disorder proposals meet criteria for clinical utility?. J Pers Disorders. 2011; 25: 192-205 [OpenAIRE] [DOI]

Phillips, J, Frances, A, Cerullo, MA, Chardavoyne, J, Decker, HS, First, MB, Ghaemi, N, Greenberg, G, Hinderliter, AC, Kinghorn, WA, LoBello, SG, Martin, EB, Mishara, AL, Paris, J, Pierre, JM, Pies, RW, Pincus, HA, Porter, D, Pouncey, C, Schwartz, MA, Szasz, T, Wakefield, JC, Waterman, GS, Whooley, O, Zachar, P. The six most essential questions in psychiatric diagnosis: a pluralogue part 1: conceptual and definitional issues in psychiatric diagnosis. Philos Ethics Humanit Med. 2012; 7: 3 [OpenAIRE] [PubMed] [DOI]

Phillips, J, Frances, A, Cerullo, MA, Chardavoyne, J, Decker, H, First, MD, Ghaemi, N, Greenberg, G, Hinderliter, AC, Kinghorn, WA, LoBello, SG, Martin, EB, Mishara, AL, Paris, J, Pierre, JM, Pies, RW, Pincus, HA, Porter, D, Pouncey, C, Schwartz, MA, Szasz, T, Wakefield, JC, Waterman, GS, Whooley, O, Zachar, P. The six most essential questions in psychiatric diagnosis: a pluralogue part 3: issues of utility and alternative approaches in psychiatric diagnosis. Philos Ethics Humanit Med. 2012; 7: 9 [OpenAIRE] [PubMed] [DOI]

Varga, S. Defining mental disorder: exploring the ‘natural function’ approach. Philos Ethics Humanit Med. 2011; 6: 1 [OpenAIRE] [PubMed] [DOI]

Nesse, RM, Stein, DJ. Towards a genuinely medical model for psychiatry. BMC Med. 2012; 10: 5 [OpenAIRE] [PubMed] [DOI]

Dictionary.com.

Sensky, T, Turkington, D, Kingdon, D, Scott, JL, Scott, J, Siddle, R, O’Carroll, M, Barnes, RE. A randomized controlled trial of cognitive-behavioral therapy for persistent symptoms in schizophrenia resistant to medication. Arch Gen Psychiatry. 2000; 57: 165-172 [OpenAIRE] [PubMed] [DOI]

NHLBI Fact Book, Fiscal Year. 2011

Hunger, SP, Lu, X, Devidas, M, Camitta, BM, Gaynon, PS, Winick, NJ, Reaman, GH, Carroll, WL. Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: A report from the children’s oncology group. J Clin Oncol. 2005; 2012 (30): 1663-1669 [OpenAIRE]

Kessler, RC, Demler, RG, Olfson, FM, Pincus, HA, Walters, EE, Wang, P, Wells, KB, Zaslavsky, AM. Prevalence and treatment of mental disorders, 1990 to 2003. N Engl J Med. 2005; 352: 2515-2523 [OpenAIRE] [PubMed] [DOI]

Hyman, SH. The diagnosis of mental disorders: the problem of reification. Ann Rev Clin Psychol. 2010; 6: 155-179 [OpenAIRE] [PubMed] [DOI]

Insel, T, Cuthbert, B, Garvey, M, Heinssen, R, Kozak, M, Pine, DS, Quinn, K, Sanislow, C, Steinberg, J, Wang, P. Research Domain Criteria (RDoC): toward a new classification framework for research on mental disorders. Am J Psychiat. 2010; 167: 748-751 [OpenAIRE] [PubMed] [DOI]

35 references, page 1 of 3
Abstract
Background Current diagnostic systems for mental disorders rely upon presenting signs and symptoms, with the result that current definitions do not adequately reflect relevant neurobiological and behavioral systems - impeding not only research on etiology and pathophysiology but also the development of new treatments. Discussion The National Institute of Mental Health began the Research Domain Criteria (RDoC) project in 2009 to develop a research classification system for mental disorders based upon dimensions of neurobiology and observable behavior. RDoC supports research to explicate fundamental biobehavioral dimensions that cut across current heterogeneous di...
Subjects
free text keywords: General Medicine, Medicine(all), Debate, Diagnosis, DSM, ICD, Psychiatric diagnosis, Psychopathology, RDoC, Research domain criteria
35 references, page 1 of 3

Wing, L, Gould, J, Gillberg, C. Autism spectrum disorders in the DSM-V: better or worse than the DSM-IV?. Res Dev Disabil. 2011; 32: 768-773 [OpenAIRE] [PubMed] [DOI]

Friedman, RA. Grief, depression, and the DSM-5. N Engl J Med. 2012; 366: 1855-1857 [PubMed] [DOI]

Skodol, AE. Personality disorders in DSM-5. Annual Rev of Clinical Psychology. 2012; 8: 317-344 [OpenAIRE] [DOI]

Clarkin, JF, Huprich, SK. Do DSM-5 personality disorder proposals meet criteria for clinical utility?. J Pers Disorders. 2011; 25: 192-205 [OpenAIRE] [DOI]

Phillips, J, Frances, A, Cerullo, MA, Chardavoyne, J, Decker, HS, First, MB, Ghaemi, N, Greenberg, G, Hinderliter, AC, Kinghorn, WA, LoBello, SG, Martin, EB, Mishara, AL, Paris, J, Pierre, JM, Pies, RW, Pincus, HA, Porter, D, Pouncey, C, Schwartz, MA, Szasz, T, Wakefield, JC, Waterman, GS, Whooley, O, Zachar, P. The six most essential questions in psychiatric diagnosis: a pluralogue part 1: conceptual and definitional issues in psychiatric diagnosis. Philos Ethics Humanit Med. 2012; 7: 3 [OpenAIRE] [PubMed] [DOI]

Phillips, J, Frances, A, Cerullo, MA, Chardavoyne, J, Decker, H, First, MD, Ghaemi, N, Greenberg, G, Hinderliter, AC, Kinghorn, WA, LoBello, SG, Martin, EB, Mishara, AL, Paris, J, Pierre, JM, Pies, RW, Pincus, HA, Porter, D, Pouncey, C, Schwartz, MA, Szasz, T, Wakefield, JC, Waterman, GS, Whooley, O, Zachar, P. The six most essential questions in psychiatric diagnosis: a pluralogue part 3: issues of utility and alternative approaches in psychiatric diagnosis. Philos Ethics Humanit Med. 2012; 7: 9 [OpenAIRE] [PubMed] [DOI]

Varga, S. Defining mental disorder: exploring the ‘natural function’ approach. Philos Ethics Humanit Med. 2011; 6: 1 [OpenAIRE] [PubMed] [DOI]

Nesse, RM, Stein, DJ. Towards a genuinely medical model for psychiatry. BMC Med. 2012; 10: 5 [OpenAIRE] [PubMed] [DOI]

Dictionary.com.

Sensky, T, Turkington, D, Kingdon, D, Scott, JL, Scott, J, Siddle, R, O’Carroll, M, Barnes, RE. A randomized controlled trial of cognitive-behavioral therapy for persistent symptoms in schizophrenia resistant to medication. Arch Gen Psychiatry. 2000; 57: 165-172 [OpenAIRE] [PubMed] [DOI]

NHLBI Fact Book, Fiscal Year. 2011

Hunger, SP, Lu, X, Devidas, M, Camitta, BM, Gaynon, PS, Winick, NJ, Reaman, GH, Carroll, WL. Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: A report from the children’s oncology group. J Clin Oncol. 2005; 2012 (30): 1663-1669 [OpenAIRE]

Kessler, RC, Demler, RG, Olfson, FM, Pincus, HA, Walters, EE, Wang, P, Wells, KB, Zaslavsky, AM. Prevalence and treatment of mental disorders, 1990 to 2003. N Engl J Med. 2005; 352: 2515-2523 [OpenAIRE] [PubMed] [DOI]

Hyman, SH. The diagnosis of mental disorders: the problem of reification. Ann Rev Clin Psychol. 2010; 6: 155-179 [OpenAIRE] [PubMed] [DOI]

Insel, T, Cuthbert, B, Garvey, M, Heinssen, R, Kozak, M, Pine, DS, Quinn, K, Sanislow, C, Steinberg, J, Wang, P. Research Domain Criteria (RDoC): toward a new classification framework for research on mental disorders. Am J Psychiat. 2010; 167: 748-751 [OpenAIRE] [PubMed] [DOI]

35 references, page 1 of 3
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