publication . Other literature type . Article . 2009

Electrical Stimulation of Nerve Cells Using Conductive Nanofibrous Scaffolds for Nerve Tissue Engineering

Laleh Ghasemi-Mobarakeh; Molamma P. Prabhakaran; Seeram Ramakrishna; Mohammad Hossein Nasr-Esfahani; Mohammad Morshed;
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  • Published: 01 Nov 2009
  • Publisher: Mary Ann Liebert Inc
Abstract
Fabrication of scaffolds with suitable chemical, mechanical, and electrical properties is critical for the success of nerve tissue engineering. Electrical stimulation was directly applied to electrospun conductive nanofibrous scaffolds to enhance the nerve regeneration process. In the present study, electrospun conductive nanofibers were prepared by mixing 10 and 15 wt% doped polyaniline (PANI) with poly (ɛ-caprolactone)/gelatin (PG) (70:30) solution (PANI/PG) by electrospinning. The fiber diameter, pore size, hydrophilicity, tensile properties, conductivity, Fourier transform infrared (FTIR), and X-ray photoelectron spectroscopy spectra of nanofibers were deter...
Subjects
Medical Subject Headings: technology, industry, and agriculture
free text keywords: Biochemistry, Bioengineering, Biomaterials, Biomedical Engineering, Electrospinning, Gelatin, food.ingredient, food, Electrical conductor, Conductivity, Ultimate tensile strength, Tissue engineering, Nanofiber, Fourier transform infrared spectroscopy, Materials science
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