publication . Article . Other literature type . 2009

Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology

Heymans, S.; Hirsch, E.; Anker, S.D.; Aukrust, P.; Balligand, J.L.; Cohen-Tervaert, J.W.; Drexler, H.; Filippatos, G.; Felix, S.B.; Gullestad, L.; ...
Open Access
  • Published: 01 Feb 2009 Journal: European Journal of Heart Failure, volume 11, pages 119-129 (issn: 1388-9842, Copyright policy)
  • Publisher: Wiley
  • Country: Netherlands
Abstract
The increasing prevalence of heart failure poses enormous challenges for health care systems worldwide. Despite effective medical interventions that target neurohumoral activation, mortality and morbidity remain substantial. Evidence for inflammatory activation as an important pathway in disease progression in chronic heart failure has emerged in the last two decades. However, clinical trials of ‘anti-inflammatory’ therapies (such as anti-tumor necrosis factor-α approaches) have to date failed to show benefit in heart failure patients. The Heart Failure Association of the European Society of Cardiology recently organized an expert workshop to address the issue o...
Subjects
free text keywords: Cardiology and Cardiovascular Medicine, Translational research, Health care, business.industry, business, Heart failure, medicine.disease, medicine, Cardiology, medicine.medical_specialty, Clinical trial, Internal medicine, Psychological intervention, Basic science, Idiopathic dilated cardiomyopathy, Myocardial infarction, Reviews
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