publication . Other literature type . Article . 2006

A tutorial on statistical methods for population association studies

David J. Balding;
  • Published: 01 Oct 2006
  • Publisher: Springer Science and Business Media LLC
Abstract
Identifying polymorphisms that are overrepresented in disease cases versus controls would seem to be a straightforward process, but genetic association studies are notoriously riddled with complex analysis problems. This article outlines these statistical issues and provides some guidance to overcoming them.
Subjects
free text keywords: Linkage disequilibrium, Quantitative trait locus, Genetic association, Population, education.field_of_study, education, Biology, Genetics, Sample size determination, Hardy–Weinberg principle, Genome-wide association study, Disease
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publication . Other literature type . Article . 2006

A tutorial on statistical methods for population association studies

David J. Balding;