publication . Other literature type . Article . 2016

Artesunate-Amodiaquine and Artemether-Lumefantrine Therapies and Selection of Pfcrt and Pfmdr1 Alleles in Nanoro, Burkina Faso

Adama Kazienga; Karim Derra; Paul Sondo; Seydou Diallo Nakanabo; Hermann Sorgho; Tinga Robert Guiguemdé; Innocent Valea; Zekiba Tarnagda; Jean-Bosco Ouedraogo; Halidou Tinto; ...
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  • Published: 31 Mar 2016
  • Publisher: Public Library of Science (PLoS)
Abstract
The adoption of Artemisinin based combination therapies (ACT) constitutes a basic strategy for malaria control in sub-Saharan Africa. Moreover, since cases of ACT resistance have been reported in South-East Asia, the need to understand P. falciparum resistance mechanism to ACT has become a global research goal. The selective pressure of ACT and the possibility that some specific Pfcrt and Pfmdr1 alleles are associated with treatment failures was assessed in a clinical trial comparing ASAQ to AL in Nanoro. Dried blood spots collected on Day 0 and on the day of recurrent parasitaemia during the 28-day follow-up were analyzed using the restriction fragments length ...
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doi: 10.1371/journal.pone.0151565
pmc: PMC4816516
pmid: 27031231
Subjects
free text keywords: Medicine, R, Science, Q, Research Article, Biology and Life Sciences, Microbiology, Microbial Control, Antimicrobial Resistance, Medicine and Health Sciences, Pharmacology, Parasitic Diseases, Malaria, Tropical Diseases, Parasitology, Parasite Groups, Apicomplexa, Plasmodium, Molecular Biology, Molecular Biology Techniques, Artificial Gene Amplification and Extension, Polymerase Chain Reaction, Research and Analysis Methods, Mathematical and Statistical Techniques, Statistical Methods, Multivariate Analysis, Physical Sciences, Mathematics, Statistics (Mathematics), Drugs, Antimalarials, Organisms, Protozoans, Parasitic Protozoans, Malarial Parasites, General Biochemistry, Genetics and Molecular Biology, General Agricultural and Biological Sciences, General Medicine, Genetics, Oncology, medicine.medical_specialty, Biology, Genotype, Plasmodium falciparum, biology.organism_classification, Single-nucleotide polymorphism, Artesunate/amodiaquine, medicine.drug, Amodiaquine, Parasitemia, medicine.disease, Artemether/lumefantrine, Internal medicine, Artemisinin
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30 references, page 1 of 2

1 WHO. Antimalarial drug combination therapy: report of a technical consultation. Geneva: 2001.

2 Tinto H, Sanou B, Dujardin J-C, Ouedraogo JB, VAN OVERMEIR C, Erhart A, et al Usefulness of the Plasmodium falciparum chloroquine resistance transporter T76 genotype failure index for the estimation of in vivo chloroquine resistance in Burkina Faso. The American journal of tropical medicine and hygiene. 2005;73(1):171–3. 16014853 [PubMed]

3 Ministry of health of Burkina Faso/PNLP. Nationale guideline for malaria cases management in Burkina Faso. 2006.

4 Tinto H, Diallo S, Zon go I, Guiraud I, Valea I, Kazienga A, et al Effectiveness of artesunate–amodiaquine vs. artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Nanoro, Burkina Faso: a non-inferiority randomised trial. Tropical Medicine & International Health. 2014;19(4):469–75.24494602 [OpenAIRE] [PubMed]

5 Noedl H, Socheat D, Satimai W. Artemisinin-resistant malaria in Asia. New England Journal of Medicine. 2009;361(5):540–1. 10.1056/NEJMc0900231 19641219 [OpenAIRE] [PubMed] [DOI]

6 Phyo AP, Nkhoma S, Stepniewska K, Ashley EA, Nair S, McGready R, et al Emergence of artemisinin-resistant malaria on the weste rn border of Thailand: a longitudinal study. The Lancet. 2012;379(9830):1960–6.

7 Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, et al Spread of artemisinin resistance in Plasmodium falciparum malaria. New England Journal of Medicine. 2014;371(5):411–23. 10.1056/NEJMoa1314981 25075834 [OpenAIRE] [PubMed] [DOI]

8 Borrmann S, Sasi P, Mwai L, Bashraheil M, Abdallah A, Muriithi S, et al Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast. PloS one. 2011;6(11):e26005 10.1371/journal.pone.0026005 22102856 [OpenAIRE] [PubMed] [DOI]

9 Tinto H, Bonkian LN, Nana LA, Yerbanga I, Lingani M, Kazienga A, et al Ex vivo anti-malarial drugs sensitivity profile of Plasmodium falciparum field isolates from Burkina Faso five years after the national policy change. Malaria journal. 2014;13(1):207.24885950 [OpenAIRE] [PubMed]

10 Ariey F, Witkowski B, Amaratunga C, Beghain J, Langlois A-C, Khim N, et al A molecular marker of artemisinin-resistant Plasmodium falciparum malaria. Nature. 2014;505(7481):50–5. 10.1038/nature12876 24352242 [OpenAIRE] [PubMed] [DOI]

11 DjimdéA, Doumbo OK, Cortese JF, Kayentao K, Doumbo S, DiourtéY, et al A molecular marker for chloroquine-resistant falciparum malaria. New England journal of medicine. 2001;344(4):257–63. 11172152 [PubMed]

12 Wongsrichanalai C, Pickard AL, Wernsdorfer WH, Meshnick SR. Epidemiology of drug-resistant malaria. The Lancet infectious diseases. 2002;2(4):209–18. 11937421 [PubMed]

13 Dahlström S, Ferreira PE, Veiga MI, Sedighi N, Wiklund L, Mårtensson A, et al Plasmodium falciparum multidrug resistance protein 1 and artemisinin-based combination therapy in Africa. Journal of Infectious Diseases. 2009;200(9):1456–64. 10.1086/606009 19807279 [OpenAIRE] [PubMed] [DOI]

14 Badolo A, Traore A, Jones CM, Sanou A, Flood L, Guelbeogo WM, et al Three years of insecticide resistance monitoring in Anopheles gambiae in Burkina Faso: resistance on the rise. Malaria journal. 2012;11(1):232.22799568 [OpenAIRE] [PubMed]

15 Ministry of health of Burkina Faso /DSN. Plan d’action 2014 du district sanitaire de Nanoro. 2013.

30 references, page 1 of 2
Related research
Abstract
The adoption of Artemisinin based combination therapies (ACT) constitutes a basic strategy for malaria control in sub-Saharan Africa. Moreover, since cases of ACT resistance have been reported in South-East Asia, the need to understand P. falciparum resistance mechanism to ACT has become a global research goal. The selective pressure of ACT and the possibility that some specific Pfcrt and Pfmdr1 alleles are associated with treatment failures was assessed in a clinical trial comparing ASAQ to AL in Nanoro. Dried blood spots collected on Day 0 and on the day of recurrent parasitaemia during the 28-day follow-up were analyzed using the restriction fragments length ...
Read more
doi: 10.1371/journal.pone.0151565
pmc: PMC4816516
pmid: 27031231
Subjects
free text keywords: Medicine, R, Science, Q, Research Article, Biology and Life Sciences, Microbiology, Microbial Control, Antimicrobial Resistance, Medicine and Health Sciences, Pharmacology, Parasitic Diseases, Malaria, Tropical Diseases, Parasitology, Parasite Groups, Apicomplexa, Plasmodium, Molecular Biology, Molecular Biology Techniques, Artificial Gene Amplification and Extension, Polymerase Chain Reaction, Research and Analysis Methods, Mathematical and Statistical Techniques, Statistical Methods, Multivariate Analysis, Physical Sciences, Mathematics, Statistics (Mathematics), Drugs, Antimalarials, Organisms, Protozoans, Parasitic Protozoans, Malarial Parasites, General Biochemistry, Genetics and Molecular Biology, General Agricultural and Biological Sciences, General Medicine, Genetics, Oncology, medicine.medical_specialty, Biology, Genotype, Plasmodium falciparum, biology.organism_classification, Single-nucleotide polymorphism, Artesunate/amodiaquine, medicine.drug, Amodiaquine, Parasitemia, medicine.disease, Artemether/lumefantrine, Internal medicine, Artemisinin
Related Organizations
Download fromView all 5 versions
PLoS ONE
Article . 2016
Provider: DOAJ-Articles
Europe PubMed Central
Article . 2016
Provider: PubMed Central
PLoS ONE
Article . 2016
Provider: Crossref
PLoS ONE
Article
Provider: UnpayWall
View more
30 references, page 1 of 2

1 WHO. Antimalarial drug combination therapy: report of a technical consultation. Geneva: 2001.

2 Tinto H, Sanou B, Dujardin J-C, Ouedraogo JB, VAN OVERMEIR C, Erhart A, et al Usefulness of the Plasmodium falciparum chloroquine resistance transporter T76 genotype failure index for the estimation of in vivo chloroquine resistance in Burkina Faso. The American journal of tropical medicine and hygiene. 2005;73(1):171–3. 16014853 [PubMed]

3 Ministry of health of Burkina Faso/PNLP. Nationale guideline for malaria cases management in Burkina Faso. 2006.

4 Tinto H, Diallo S, Zon go I, Guiraud I, Valea I, Kazienga A, et al Effectiveness of artesunate–amodiaquine vs. artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Nanoro, Burkina Faso: a non-inferiority randomised trial. Tropical Medicine & International Health. 2014;19(4):469–75.24494602 [OpenAIRE] [PubMed]

5 Noedl H, Socheat D, Satimai W. Artemisinin-resistant malaria in Asia. New England Journal of Medicine. 2009;361(5):540–1. 10.1056/NEJMc0900231 19641219 [OpenAIRE] [PubMed] [DOI]

6 Phyo AP, Nkhoma S, Stepniewska K, Ashley EA, Nair S, McGready R, et al Emergence of artemisinin-resistant malaria on the weste rn border of Thailand: a longitudinal study. The Lancet. 2012;379(9830):1960–6.

7 Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, et al Spread of artemisinin resistance in Plasmodium falciparum malaria. New England Journal of Medicine. 2014;371(5):411–23. 10.1056/NEJMoa1314981 25075834 [OpenAIRE] [PubMed] [DOI]

8 Borrmann S, Sasi P, Mwai L, Bashraheil M, Abdallah A, Muriithi S, et al Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast. PloS one. 2011;6(11):e26005 10.1371/journal.pone.0026005 22102856 [OpenAIRE] [PubMed] [DOI]

9 Tinto H, Bonkian LN, Nana LA, Yerbanga I, Lingani M, Kazienga A, et al Ex vivo anti-malarial drugs sensitivity profile of Plasmodium falciparum field isolates from Burkina Faso five years after the national policy change. Malaria journal. 2014;13(1):207.24885950 [OpenAIRE] [PubMed]

10 Ariey F, Witkowski B, Amaratunga C, Beghain J, Langlois A-C, Khim N, et al A molecular marker of artemisinin-resistant Plasmodium falciparum malaria. Nature. 2014;505(7481):50–5. 10.1038/nature12876 24352242 [OpenAIRE] [PubMed] [DOI]

11 DjimdéA, Doumbo OK, Cortese JF, Kayentao K, Doumbo S, DiourtéY, et al A molecular marker for chloroquine-resistant falciparum malaria. New England journal of medicine. 2001;344(4):257–63. 11172152 [PubMed]

12 Wongsrichanalai C, Pickard AL, Wernsdorfer WH, Meshnick SR. Epidemiology of drug-resistant malaria. The Lancet infectious diseases. 2002;2(4):209–18. 11937421 [PubMed]

13 Dahlström S, Ferreira PE, Veiga MI, Sedighi N, Wiklund L, Mårtensson A, et al Plasmodium falciparum multidrug resistance protein 1 and artemisinin-based combination therapy in Africa. Journal of Infectious Diseases. 2009;200(9):1456–64. 10.1086/606009 19807279 [OpenAIRE] [PubMed] [DOI]

14 Badolo A, Traore A, Jones CM, Sanou A, Flood L, Guelbeogo WM, et al Three years of insecticide resistance monitoring in Anopheles gambiae in Burkina Faso: resistance on the rise. Malaria journal. 2012;11(1):232.22799568 [OpenAIRE] [PubMed]

15 Ministry of health of Burkina Faso /DSN. Plan d’action 2014 du district sanitaire de Nanoro. 2013.

30 references, page 1 of 2
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