Recurrent brief depression is a new diagnostical entity recently individualized among depressive disorders and characterized by repeated brief depressive episodes of a few days duration at least once a month over one year. The disorder generally of early onset seems to be present in 14.6% of the population up to 35 years and is associated with marked family and social disturbances as well as with a high rate of suicide attempts. The adequate treatment of recurrent brief depression has still to be defined and fluoxetine-type antidepressants appear devoid of efficacy.