Pharmacokinetics of metamizol metabolites.

Name: Pharmacokinetics of metamizol metabolites.
Creator: M, Levy
Keywords: 0301 basic medicine, Male, 0303 health sciences, Metabolic Clearance Rate, Dipyrone, Acetylation, 3. Good health, 03 medical and health sciences, Humans, Female

M, Levy

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Article . 1986

Data sources: Europe PubMed Central

Pharmacokinetics of metamizol metabolites.

descriptionPublicationkeyboard_double_arrow_right Article 07 Oct 1986 English Journal:Agents and actions. Supplements, volume 19 (issn: 0379-0363,

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Authors: M, Levy;

pmid: 3463178

Pharmacokinetics of metamizol metabolites.

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Abstract

When administered to humans, metamizol rapidly undergoes predominantly nonenzymatic biotransformation, yielding a vast number of active and later inactive metabolites. The biotransformational pathways and the clinical significance of the metabolites are discussed in the light of their individual pharmacokinetics.

Keywords

Male, Metabolic Clearance Rate, Dipyrone, Acetylation, Humans, Female, Aminopyrine, Biotransformation, Chromatography, High Pressure Liquid, Protein Binding

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