Merocyanines: potential new anticancer agents.

We report the synthesis of a series of merocyanines and the structure-effect relationship as cytotoxic agents for human adenocarcinoma cells in vitro. The cytotoxicity of these compounds in vitro makes them potential anticancer agents. One of these compounds was found active on human and mouse tumor models.

Keywords

Structure-Activity Relationship, Pyridines, Tumor Cells, Cultured, Humans, Antineoplastic Agents, Adenocarcinoma

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