
Phosphodiesterase III inhibitors constitute a new therapeutic group for congestive cardiac failure. They inhibit the degradation of cyclic adenosine monophosphate and increase the intracellular calcium. They have a double inotropic and vasodilator haemodynamics occurs without any increase in the myocardial effect. The improvement in the consumption of oxygen. The beneficial haemodynamic effect seems to last over a medium period of time, but the survival in the long term treatment is not yet known.
Electrophysiology, Heart Failure, Oxygen Consumption, Phosphodiesterase Inhibitors, Humans, Kidney
Electrophysiology, Heart Failure, Oxygen Consumption, Phosphodiesterase Inhibitors, Humans, Kidney
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