A median defect in the region of the root of the nose, in between the two orbits, was discovered in the dried skull of a 44-year-old female cadaver, during routine undergraduate teaching. The two small nasal bones articulated with each other and the cribriform plate of the ethmoid. The lacrimal bones and frontal processes of the maxillary bones were also deformed. We propose that the median defect was due to abnormality at the fonticulus frontalis, the prenasal space and the interorbitonasal part of the nasal capsule, as well as defects in the ossification of the maxilla, lacrimal and frontal bones.