This chapter examines how the agenda of prevention of armed conflict relates to the principle of the responsibility to protect (R2P). While R2P was originally assumed to be fully compatible with the goals and principles of traditional conflict prevention, subsequent research has disentangled the relationship between R2P and conflict prevention, arguing that conflict prevention is a necessary but not a sufficient component of atrocity prevention, and that atrocity prevention needs to include a strategy for deterring potential perpetrators. Recent scholarship has started to examine the implications of marrying R2P to international criminal law categories. What follows from R2P’s move to crimes is an individualization of the principle, as well as a shift towards partiality, intrusion, and coercion. This means that where a threat of atrocity crimes occurs in the context of armed conflict, it cannot simply be assumed that R2P and conflict prevention are pulling in the same direction. The research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013) / ERC Grant Agreement No 340956 - IOW - The Individualisation of War: Reconfiguring the Ethics, Law, and Politics of Armed Conflict.