p75NTR is positively promiscuous: novel partners and new insights.
Copyright policy )p75NTR is positively promiscuous: novel partners and new insights.
Although identified almost 20 years ago, the precise physiological role of the p75 neurotrophin receptor (p75NTR) has remained elusive. Recent studies have revealed that p75NTR is a component of three distinct receptor platforms that bind different ligands and that, under differing circumstances, facilitate cell survival, cell death, or growth inhibition. These recent developments provide new insights into the functions of this enigmatic receptor.
Membrane Glycoproteins, Cell Death, Cell Survival, Nogo Proteins, Nerve Tissue Proteins, Receptors, Nerve Growth Factor, Ligands, Nervous System, Receptor, Nerve Growth Factor, Sortilin, Adaptor Proteins, Vesicular Transport, Animals, Humans, Nerve Growth Factors, Myelin Proteins, Protein Binding
Membrane Glycoproteins, Cell Death, Cell Survival, Nogo Proteins, Nerve Tissue Proteins, Receptors, Nerve Growth Factor, Ligands, Nervous System, Receptor, Nerve Growth Factor, Sortilin, Adaptor Proteins, Vesicular Transport, Animals, Humans, Nerve Growth Factors, Myelin Proteins, Protein Binding
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