Pitted keratolysis is a superficial infection of the skin confined to the stratum corneum. The causative organism has not been identified. The clinical syndrome is distinct and is characterized by pits and superficial erosions in the pressure areas of the soles and in the lateral surfaces of the toes. The histopathology of the lesions is presented and world literature is reviewed. It is concluded that this disease is not limited to the tropical climates, although cases tend to be more severe in these areas.