Cystic echinococcosis (CE) is a major public health problem in Turkey. Serological confirmation of CE cases has not standardized at present. In our study, sera were taken from 150 surgically confirmed CE patients, 71 patients with non-parasitic cysts, tumours, abscess, allergy or lymphadenopathy, also sera from 35 patients infected with intestinal and tissue helminths and 30 healthy people as control group. A total of 286 sera was studied by Western blotting (WB), Indirect Fluorescent Antibody Test (IFAT), Indirect Haemaglutination Test (IHAT), and Enzyme Linked Immunosorbent Assay (ELISA). Specificity and sensitivity were found as follows; 94.7 % and 91.9 % by IFAT; 94.7 % and 94.1 % by IHAT; 96.7 % and 92.6 % by ELISA and 96.0 % and 100 % by WB. It was found that ELISA had the highest 96.7 % sensitivity and on the other hand WB had the highest 100 % specificity for human CE antibody detection.

WOS: 000181894800002