Epilepsy aff ects about 0.5-1.5% of the population, of which approximately 30% of patients are drugresistant.The importance of MRI in dia gnosis lies mainly in the detection of structural etiology of the disease, assessing the patient‘s prognosis and, to a limited extent, planning appropriat treatment. Despite technological advances and technical equipment in medical centers, there is a considerable inconsistency in the MRI protocols used for structural brain imaging in patients with epilepsy. We aim to recommend a standardized MR structural brain imaging protocol for patients with epilepsy based on current international recommendations. Its widespread implementation will enable the establishment of a unified neuroimaging platform in the Czech Republic for these indications.