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Biblioteca Digital - Universidad Icesi
Master thesis . 2014
License: CC BY NC ND
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Cultivo in vitro de tejidos vegetales de plantas del género zephyranthes y evaluación de su producción de alcaloides.

Authors: Peralta Navarro , Luis Alberto;

Cultivo in vitro de tejidos vegetales de plantas del género zephyranthes y evaluación de su producción de alcaloides.

Abstract

Las Amaryllidaceae son una familia de plantas bulbosas y perennes las cuales han sido ampliamente conocidas por su valor ornamental. El estudio de esta familia ha aumentado desde 1950 y una de las razones se debe a la gran utilidad farmacéutica que han presentado los alcaloides presentes en dichas plantas. Se han identificado algunos géneros ubicados en el Valle del Cauca que se han visto en peligro de extinción debido a la destrucción de su hábitat como el caso de Eucharis y Caliphruria (en ejemplo C. hartwegiana y C. subedentata); además de otros géneros como Phaedranasa, Sprekelia, Hippeastrum y Crinum. Los dos principales alcaloides reportados para la familia Amaryllidaceae son la galantamina y la licorina. El mecanismo de acción de estas moléculas se basa en la inhibición enzimática de la acetil colinesterasa, exhibiendo aplicación farmacéutica en enfermedades neurodegenerativas como el Alzheimer. Otros alcaloides como Haemantamina, Vittatina y tazetina entre otros, han presentado actividad antiinflamatorio, anti-malárico y antibacterial.

The Amaryllidaceae is a family of bulbous and perennial plants which have been widely known for their ornamental value. The study of this family in the last decade has increased; one reason is because of the large pharmaceutical potential that possesses the alkaloids present in these plants. Genres of this family found in the Valle del Cauca have been endangered due to habitat destruction such as Eucharis and Caliphruria (for example C. hartwegiana and C. subedentata). In addition, other genres like Phaedranasa, Sprekelia, Hippeastrum and Crinum. The Amaryllidaceae alkaloids reported in greater abundance are Licorine and Galantamine. The mechanism of action of these molecules is based on inhibition of the enzyme acetylcholinesterase, showing pharmaceutical use in neurodegenerative diseases such as Alzheimer's. Other alkaloids such Haemantamina, Vittatina and tazetina among others, have presented anti-inflammatory activity, antimalarial and antibacterial

Country
Colombia
Related Organizations
Keywords

Farmacéutica, Hábitat, Biología, Valle del Cauca (Colombia), Química Farmacéutica, Moléculas, Plantas, Tejidos, Facultad de Ciencias Naturales, Alcaloides, Departamento de Ciencias Químicas, Producción intelectual registrada - Universidad Icesi, Cultivo, Biology

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green