Nanoscale surface treatments and their effect on liquid film pinning and thin film evaporative heat transfer was studied through published literature and experimental simulation. ANSYS Fluent was utilized to study relevant geometries and to confirm experimental results found in published literature. Vapor chambers were studied to compare their current performance to that of a vapor chamber with a proposed graphene integrated CIO, copper inverse opal, wicking structure. The role of graphene in altering the surface energy and conductive characteristics of a given substrate as well as its performance as a protective coating was studied, yielding results that require further study. Further research will be required to confirm published results on the wettability of graphene as well as building a two-phase fluid flow simulation to study the performance of copper inverse opal wicking structures.