The PHOENIX Open Innovation Test Bed (PHOENIX-OITB) is focused on overcoming the challenges of production of novel and innovative nanopharmaceuticals (NPs) from lab scale to GMP quality and production, maximising bioavailability, stability and manufacturing to allow their implementation in the medicine field. PHOENIX-OITB is a non-profit, open and self-sustaining legal entity that works as a Single-Entry-Point (SEP) providing its end-users transparent processes and procedures as well as easy access to services and expertise needed to bridge the gap between the bench and the bedside, i.e., providing them with high-quality services, capable of Quality-Efficacy and Safety (QES) evaluation and production of nanopharmaceuticals at large scales meeting the regulatory and GMP requirements.