ABSTRACT Diabetes is a chronic metabolic disease that affects millions of people worldwide. The prevalence of diabetes has been increasing rapidly, with estimates projecting that 783 million people worldwide will have diabetes by 2045. The United States has also seen a significant rise in diabetes cases, with over 34 million people living with the disease. This article presents a clinical case of a 48-year-old male patient with a 10-year history of diabetes and hyperlipidemia, who was insulin dependent and taking metformin and atorvastatin. Despite these medications, the patient's A1C was 9.5, and his doctor was considering increasing his insulin dose. Additionally, the patient reported experiencing peripheral neuropathy and chronic pain in his lower extremities and behind his knees. The patient reached out to Dr. Eduardo Beltran and was introduced to the protocol and underwent a 12-month period treatment with the LGS Protocol, which involved taking 50,000 IU of vitamin D3 daily, along with cofactors and 600 mg of alpha-lipoic acid BID. The patient was able to lose over 45 pounds during this period and continues to do so. Medications were gradually discontinued. By month 4, the patient no longer required any medications and continued taking only the supplements of the protocol. After 12 months into the protocol, his A1C was significantly reduced to 5.6. The patient is now in complete remission. This case study highlights the potential benefits of a holistic approach to managing diabetes, which focuses on lifestyle modifications, diet, and natural interventions. The LGS Protocol, which emphasizes the importance of adequate vitamin D levels, alpha-lipoic acid, and healthy eating habits, has shown promising results in helping patients achieve better outcomes. These findings suggest that a comprehensive approach to diabetes management may be a viable alternative to traditional medications and help patients achieve long-term remission.