ABSTRACT Flavanones are a diverse group of phytonutrients found in most plants. They act as pigments, producing many colours like yellow, red and orange found in plant-based diets. Flavanones have become an essential component in a wide range of nutraceutical, pharmacological, therapeutic, and cosmetic applications. This is due to their ability to control critical cellular enzyme activity as well as their anti-inflammatory, Flavanones were discovered in 1938 by a Hungarian scientist named Dr. Albert Szent-Gyorgyi, who identified them as vitamin P. The challenge is that the chemistry of Flavanones is difficult because there are over 6,000 distinct compounds that belong to the flavonoid family. These challenges could be overcome by optimization techniques, novel technology, fermentation and metabolic engineering. The functional recommendations that could be added here are population heterogeneity, high study cost and time. Many different chemical families of compounds such as Flavonols, dihydroflavonols, flavones, isoflavones, flavanones, anthocyanins, and anthocyanidins are among these groups. Hundreds, if not thousands, of distinct Flavanones can be found in each of these families. Examples of some well-known flavonols include quercetin, rutin, and hesperidin while well-known apigenin and luteolin. Keywords: Flavanones, Antimicrobial activity, Anticancer activity, Bio Flavanones, Antibacterial characteristics.