The brain tumor accounts for 2 percent among all cancers in adults from across the globe. The most common brain tumor is glioblastoma multiforme, and patients with this type of tumor have a poor prognosis. The exposure to high ionizing radiation has only proven to be a one of risk factor for brain tumor. The classification of brain tumor is done depending upon their cellular origin and histological appearance. The typical symptoms of brain tumor include headache, seizures, nausea, vomiting, neurocognitive symptoms, and personality changes as well. The diagnosis of brain tumor is done by imagining and is confirmed by study of histopathology. Any person with chronic, persistent headache in association with protracted nausea, vomiting, seizures, change in headache pattern, neurologic symptoms, or positional worsening should be evaluated for a brain tumor. MRI is used technology for the primary imagining study of sample. A comprehensive neurosurgical evaluation is necessary to obtain tissue for diagnosis and for possible resection of the tumor. The primary stage brain tumor hardly metastasizes outside central nervous system, and no standard method is yet developed to identify it. Surgical resection of the tumor is the mainstay of therapy. Postoperative radiation and chemotherapy have improved survival in patients with high-grade brain tumors. Recent developments in targeted chemotherapy provide novel treatment options for patients with tumor recurrence.