Abstract Nasosinusal polyposis is a chronic inflammatory disease of the mucosa of the ethmoid sinuses, appearing mostly as bilateral polypoid lesions. On the other hand, NSAID- Exacerbated respiratory disease (NERD, also known as Widal’s triad) includes this pathology, as well as asthma and intolerance to aspirin and/or NSAIDs. Here, we determined that the prevalence of NERD is only 6% of the patients in the study (n = 70), with no predominant sex. Furthermore, a higher prevalence of nasosinusal polyps was found in male patients (63%), with an average near 40 years old. The most common symptom is nasal obstruction, followed by watery rhinorrhea and headache. The presence of polyps was confirmed to be bilateral in most cases, being 6% unilateral. This is the first study carried out in Paraguay on the prevalence of this disease, which will lay the foundations for future research.