publication . Article . 2020

The Organoid Cell Atlas: A Rosetta Stone for Biomedical Discovery and Regenerative Therapy

Bock, Christoph; Boutros, Michael; Camp, J. Gray; Clarke, Laura; Clevers, Hans; Knoblich, Juergen A.; Liberali, Prisca; Regev, Aviv; Rios, Anne C.; Stegle, Oliver; ...
Open Access English
  • Published: 30 Aug 2020
Abstract
Human organoids – three-dimensional structures of cells that recapitulate important aspects of organ development in vitro – hold tremendous potential for biomedical applications. To help deliver on the promises of combining human organoids with single-cell technology, we have launched an Organoid Cell Atlas pilot project, as a ‘Biological Network’ within the Human Cell Atlas (HCA), focusing on single-cell profiling of organoids and in vitro cell models (https://www.humancellatlas.org/coordinators/). The Organoid Cell Atlas will foster the production, quality control, dissemination, and utilization of single-cell and spatial genomics data for human organoids, and...
Subjects
free text keywords: Organoids, Single-cell profiling, High-throughput imaging, Multi-omics technology, Data resources, Bioinformatic tools, Integrative analysis, Biomedical applications, Organoids, Single-cell profiling, High-throughput imaging, Multi-omics technology, Data resources, Bioinformatic tools, Integrative analysis, Biomedical applications
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Article . 2020
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Article . 2020
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Article . 2020
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