New two-dimensional transition metal carbides called MXenes hold great promise for future applications in many science and technology areas. Unique compound of characteristics of MXenes such as conductivity, strength, hydrophilicity and electromagnetic interference (EMI) shielding give a possibility to create new high-tech multifunctional composite materials. As an example, conductive MXene/polymer nanocomposites with these unique properties could be used for structural health monitoring in an airplane wing or a wind turbine blade. The complexity in degradation process of composites filled with nanoinclusions brings a challenge for experimentalists. In order to understand the evolution of damage and determine mechanical properties, finite element (FE) modelling at microscale level can be useful. The aim of this study was to find the mechanical properties of a single MXene nanosheet and interface layer between nanofiller and polymer matrix using strategy of inverse finite element modelling under static and dynamic loading.