The Project Handbook provides a complete overview of the management and administrative procedures and principles to ensure an efficient execution of the BY-COVID project, thus contributing to the production of high quality project results. It contains all relevant planning information that the consortium partners will use as a framework for delivery during the course of the project, therefore, it is the point of reference for all consortium partners and stakeholders. The Project Handbook documents the selected approach for implementing the project goals, including the milestones, deliverables and relevant KPIs. It also highlights the key controlling processes to be used, the project policies and rules, and the overall management approach, including, but not limited to management structure, tasks, decision-making procedures, responsibilities and roles. Language adopted throughout the documents aims to be clear and concise. The Project Handbook is kept up to date throughout the life of the project through annual revisions. This is a guidance document. It should not be relied upon for making any legal assessments, for which Beneficiaries should always refer to the Grant Agreement (including its annexes) and the Consortium Agreement.