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comparison of oxford nanopore basecalling tools

Authors: Ryan Wick; Louise M Judd; Kathryn E Holt;

comparison of oxford nanopore basecalling tools

Abstract

This repository uses a bacterial genome to assess the read accuracy and consensus sequence accuracy for Oxford Nanopore Technologies (ONT) basecallers. Albacore v2.1.2 and Scrappie raw v1.1.1 (both developed by ONT) were the best overall performers, and Chiron v0.2 was the best performing third-party basecaller. Consensus sequence accuracies reached approximately 99.5%, revealing that even the best basecallers still have systematic errors. Nanopolish, used with its methylation-aware option, was able to raise consensus accuracy to about 99.9%.

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
15
Top 10%
Top 10%
Top 10%
Green