publication . Conference object . Other literature type . 2016

Visualising the parasitic whipworm Trichuris muris using X-ray micro-computed tomography

O'Sullivan, James; Else, Kathryn; Behnsen, Julia; Starborg, Tobias; Cruickshank, Sheena; Macdonald, Andrew; Withers, Philip;
Open Access English
  • Published: 07 Sep 2016
<p>Trichuriasis is a tropical disease that affects an estimated 500 million people worldwide, especially children in tropical regions. It is caused by a parasitic nematode, Trichuris trichiura (whipworm). Current drugs lack efficacy, and there is no vaccine. Adult worms live partially buried in the mucosal epithelium of the intestine of the host, which makes them hard to study by traditional microscopy methods. As a consequence, little is known about how they feed, develop, and avoid the immune response of the host.</p> <p>Micro X-ray CT of largely intact sections of intestine allows studying the intimate relationship between the parasite and host epithelium whi...
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free text keywords: Uncategorized, zenodo, trichuris muris, trichiuriasis, whipworm, parasite, nematode, gut, intestine, micro-CT, CT, microcomputed tomography
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Conference object . 2016
Provider: Datacite
Other literature type . 2016
Provider: Datacite
Conference object . 2016
Provider: figshare
Conference object . 2016
Provider: ZENODO
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