publication . Article . 2019

Study of the side effects of Docetaxel as chemotherapy medicine on changing the expression of genes of Enterococcus faecalis isolated from patients with breast cancer

Farnaz Rahbarzare; Elham Eslahi; Nazafarin Hatami-Mazinani; Elham Magharehabed; Mahsa Aliqanbari; Niloofar Ahmadi; Shabnam Naderifar; Mona Mirgeloybayat; Hamed Hojatian; Mojdeh Naeima; ...
Open Access
  • Published: 04 Feb 2019
  • Publisher: Zenodo
Abstract
The present study strived to ascertain the side effects of chemotherapy on the pathogenic potential of Enterococcus faecalis (a natural microflora bacteria) isolated from patients with breast cancer. Participants included 400 female sufferers from breast cancer before and after the period of chemotherapy and 400 healthy people living with patients.After RNA extracted from the stool of all the participants, cDNA was constructed. Nineteen virulent genes (vanB, vanA, VanC-3,VanC-2, VanC-1, aac(6′)-Ie-aph(2″)-Ia, Tet(L), Erm(B), gelE, esp, gyrA,slyA, cylA,cylB,cylM, asa1, aggA, efaA and enlA) of E. faecalis were assessed by Real-Time qPCR. The findings revealed a st...
Subjects
Medical Subject Headings: biochemical phenomena, metabolism, and nutrition
free text keywords: Breast cancer, Docetaxel, antibiotic resistance, Enterococcus faecalis, Breast cancer, Docetaxel, antibiotic resistance, Enterococcus faecalis
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Open Access
Zenodo
Article . 2019
Provider: Datacite
Open Access
ZENODO
Article . 2019
Provider: ZENODO
Open Access
Zenodo
Article . 2019
Provider: Datacite
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