Abstract There is currently an increase in activity in missions to the lunar surface. Until 2030, as part of the Artemis program (USA), it is planned to land astronauts on the lunar surface. The next step in the exploration of the Moon logically follows the creation of a permanent inhabited station on its surface. The article solves the problem of creating a structural and technological system for a residential module for lunar conditions using lunar regolith as the main building and thermal insulation material. The proposed design solves the problem of providing comfortable temperature conditions and protection from micrometeorites and penetrating radiation. Keywords: ADDIE model; core literacy in biology; laboratory instruction