Monitoring physiological and behavioural data related to the five domains of well-being (i.e., physical, mental, cognitive, social, and nutritional) is relevant for assessing the profile of people using assistive technologies, in order to provide early detection and adaptive support to his changing individual needs related to ageing. In this paper, we present a system called NESTORE that aims at addressing such a challenge. In particular, we focus on the enabling technology that composes the core set of devices of the so-called environmental monitoring system, namely the NESTORE Bluetooth Low Energy beacons. The presented system performs a range of services including data collection and analysis of short- and long-term trends in social and behavioural parameters. Furthermore, using the same set of devices the system provides insights on the status of the user’s vital space in terms of thermal comfort. We provide an overview of the NESTORE environmental monitoring system and details and evaluation of the software modules built upon the chosen technology: social interaction detection, indoor behavioural index inference, and indoor thermal comfort detection.