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Revista Eletrônica de Farmácia
Article . 2008 . Peer-reviewed
Data sources: Crossref
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Revista Eletrônica de Farmácia
Article
License: CC BY NC
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EFEITO DA SUPLEMENTAÇÃO ALIMENTAR SOBRE AÇÃO ANABÓLICA DO DECANOATO DE NANDROLONA EM RATOS

Authors: Ricardo Sá Fermo; Juliana N. I. Rego; João Vicente M. Franquini; Tadeu Uggere Andrade;

EFEITO DA SUPLEMENTAÇÃO ALIMENTAR SOBRE AÇÃO ANABÓLICA DO DECANOATO DE NANDROLONA EM RATOS

Abstract

Embora existam aplicacoes clinicas de esteroides anabolicos androgenicos (EAA), tambem ha abuso generalizado destas drogas por estarem relacionadas ao aumento do tamanho e forca muscular. O uso indevido de EAA, hormonio de crescimento e ergogenicos e um problema complexo, pois conduziu ao abuso destes compostos, a principio por competidores de alto nivel, alcancando tambem areas de atividade fisica em geral. Este trabalho tem por objetivo avaliar o efeito anabolico do EAA e se este efeito sofre influencia de suplementacao alimentar, mesmo em condicoes sedentarias. Utilizou-se ratos WISTAR que foram divididos em quatro grupos. Grupos DECA: receberam tratamento com decanoato de nandrolona (DN), em duas doses semanais de 10 mg. Kg-1 cada; DECAS: receberam a mesma dose de DN e suplementacao alimentar, na dose de 0,86 ml/kg; CON: receberam apenas o veiculo (oleo de amendoim) na mesma dose que DN; CONS: receberam o mesmo volume do veiculo e a mesma dose do suplemento alimentar. Todos os animais foram tratados por 4 semanas. Determinou-se o teor de proteina e lipideo corporais atraves das tecnicas de Kjeldahl e Soxhlet, respectivamente. Os resultados encontrados neste estudo demonstraram aumento da sintese proteica muscular (CON: 17,4% ± 1,344; CONS: 18,6% ± 1,289; DECA: 27,6% ± 0,935; DECAS: 36,4% ± 0,613) e diminuicao do teor de lipideos corporais (CON: 26,1%± 2,460; CONS: 29,1%± 1,027; DECA: 21,8%± 0,701; DECAS: 23,2%± 1,509). Portanto, conclui-se que a suplementacao alimentar utilizada reforca o efeito anabolico do DN por meio de uma acao sinergica no aumento do teor de proteina. 10.5216/ref.v5i1.4621

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
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