Orthodontists treat malocclusions by applying three-dimensional forces. For years, the diagnosis of this three-dimensional condition and the related treatment plan has been based on two-dimensional imaging. Lateral and anteroposterior cephalometric, panoramic, and periapical radiographs are some of the two-dimensional radiographs routinely used in orthodontics. Despite being highly beneficial in evaluating skeletal and dental relations, these radiographs fail to provide sufficient two-dimensional information in certain cases. The purpose of this compilation is to review the use of cone-beam computed tomography in orthodontics.