publication . Article . 2021

B cell depletion in immune-mediated rheumatic diseases and coronavirus disease 2019 (COVID-19)

E. L. Nasonov; A. S. Avdeeva;
Open Access
  • Published: 06 Sep 2021 Journal: Rheumatology Science and Practice, volume 59, pages 384-393 (issn: 1995-4484, eissn: 1995-4492, Copyright policy)
  • Publisher: Mediar Press
In patients with immune-mеdiated (autoimmune) rheumatic diseases (IMIRD), there are a number of factors (advanced age, uncontrolled inflammation, initially irreversible damage to internal organs, comorbid pathology, genetic and other factors) that can potentially lead to an increase in “sensitivity” to SARS-CoV -2 (severe acute respiratory syndrome coronavirus-2) and concomitant viral and bacterial infections, an increase in the risk of a severe course of COVID-19 (coronavirus disease 2019), a decrease in the effectiveness of therapy for both IMIRDs and COVID-19. An important area of pharmacotherapy for IMIRDs and other autoimmune diseases is associated with the...
Persistent Identifiers
free text keywords: Immunology, Immunology and Allergy, Rheumatology
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